All aggressive Cancer cells produce abnormal amounts of acid as part of their high growth rate and invasive processes.
Cancer cells in order to remain viable need to pump these high levels of acid across the cell membrane to the exterior microenvironment.
Proton Pump Inhibitors have been found in laboratory tests to impede the removal of acids from cancer cells which reduces their viability. This results in cell death and Tumour shrinkage.
Improving the delivery of these Proton Pump Inhibitors to cancer sites is a major challenge.
We have found a novel formulation NACO which significantly increases the transport and consequently the effectiveness of the Proton Pump Inhibitor.